Floxoptho DX Eye Drops
Floxoptho DX Eye Drops
Composition: Moxifloxacin Hydrochloride eq to Moxifloxacin 0.5% w/v + Dexamethasone Sodium Phosphate eq to Dexamethasone Phosphate 0.1% w/v
Formulation: Eye Drops
Category: Antibiotic + Corticosteroid
Packaging: 5ML
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Floxoptho DX Eye Drops
Description
Therapy/Class: Antibiotic + Corticosteroid
Mechanism of Action:
Moxifloxacin: An 8-methoxy advanced generation fluoroquinolone that optimally inhibits both Topoisomerase II and Topoisomerase IV. The methoxy group at the C-8 position minimizes the selection of resistant mutants and broadens coverage against atypical, Gram-positive, and Gram-negative organisms in ocular infections.
Dexamethasone: A highly efficacious, long-acting synthetic glucocorticoid that rapidly permeates the corneal epithelium to suppress cellular exudation, capillary permeability, and fibroblastic proliferation. It achieves potent suppression of the immune response by inhibiting the transcription of pro-inflammatory genes.
Indications
Treatment of bacterial conjunctivitis caused by susceptible organisms
Superficial ocular bacterial infections as advised by the treating ophthalmologist
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Stroman DW, et al. In vitro and in vivo efficacy of moxifloxacin and gatifloxacin against ocular pathogens. Surv Ophthalmol. 2005;50 Suppl 1:S16-24.
2. O’Brien TP, et al. Antibacterial susceptibility of conjunctival bacterial isolates: A ten-year review. Clin Ophthalmol. 2007;1(3):341-348.
1. Notivol R, et al. Efficacy and safety of dexamethasone in ophthalmic suspensions. Am J Ophthalmol. 2004;137(4):780-781.
Warning: This information is only for the use of registered medical practitioners only.
