Opthofml T Eye Drops
Opthofml T Eye Drops
Composition: Tobramycin Sulphate eq to Tobramycin 0.3% w/v + Fluorometholone 0.1% w/v
Formulation: Eye Drops
Category: Antibiotic + Corticosteroid
Packaging: 5ML
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Opthofml T Eye Drops
Description
Therapy/Class: Antibiotic + Corticosteroid
Mechanism of Action:
Tobramycin: A water-soluble aminoglycoside that irreversibly binds to the 30S subunit of the bacterial ribosome, inducing mRNA misreading. It exhibits excellent bactericidal activity, specifically functioning as a critical clinical tool against severe Gram-negative bacilli keratitis and conjunctivitis.
Fluorometholone: A potent fluorinated glucocorticoid providing robust suppression of anterior segment inflammation. Notably, it exhibits limited intraocular penetration compared to ketone steroids, presenting a distinctly safer clinical profile regarding IOP spikes in steroid-responders.
Indications
Treatment of bacterial conjunctivitis caused by susceptible organisms
Superficial ocular bacterial infections as advised by the treating ophthalmologist
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Wilhelmus KR, et al. Tobramycin drops vs ointment in ocular infections. Am J Ophthalmol. 1987;104(3):284-288.
2. Mather R, et al. Fourth-generation fluoroquinolones and aminoglycoside synergy. Am J Ophthalmol. 2002;133(4):463-466.
1. Akingbehin T, et al. Fluorometholone versus dexamethasone in the treatment of allergic conjunctivitis and their effect on intraocular pressure. Br J Ophthalmol. 1991;75(9):527-530.
Warning: This information is only for the use of registered medical practitioners only.
