Patoptho KT Eye Drops
Patoptho KT Eye Drops
Composition: Olopatadine 0.1% w/v + Ketorolac Tromethamine 0.5%w/v
Formulation: Eye Drops
Category: Anti-Allergic + NSAID
Packaging: 5ML
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Patoptho KT Eye Drops
Description
Therapy/Class: Anti-Allergic + NSAID
Mechanism of Action:
Ketorolac Tromethamine: A direct, non-selective COX inhibitor that prevents the conversion of arachidonic acid to endoperoxides. This halts the prostaglandin-mediated inflammatory cascade, significantly raising the nociceptive threshold (reducing pain) and preventing surgically induced miosis and cystoid macular edema.
Olopatadine: A dual-action pharmacological agent that selectively antagonizes H1 receptors while stabilizing the mast cell lipid bilayer. It prevents calcium influx, thus blocking the exocytosis of preformed histamine and newly synthesized inflammatory lipid mediators (prostaglandin D2).
Indications
Management of post-surgical anterior segment inflammation
Reduction of ocular pain following ophthalmic surgery
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Flach AJ, et al. Effectiveness of ketorolac tromethamine 0.5% ophthalmic solution for chronic aphakic and pseudophakic cystoid macular edema. Am J Ophthalmol. 1987;103(4):479-486.
2. Bucci FA, et al. Ketorolac tromethamine in the reduction of ocular pain following refractive surgery. Cornea. 2008;27(8):919-922.
1. Abelson MB, et al. Tolerance and efficacy of olopatadine hydrochloride ophthalmic solution 0.1%. Am J Ophthalmol. 1998;125(6):797-804.
Warning: This information is only for the use of registered medical practitioners only.
