Tobroptho D Eye Drops
Tobroptho D Eye Drops
Composition: Dexamethasone 0.1% w/v + Tobramycin Sulphate 0.3% w/v
Formulation: Eye Drops
Category: Antibiotic + Corticosteroid
Packaging: 10ML
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Tobroptho D Eye Drops
Description
Therapy/Class: Antibiotic + Corticosteroid
Mechanism of Action:
Dexamethasone: A highly efficacious, long-acting synthetic glucocorticoid that rapidly permeates the corneal epithelium to suppress cellular exudation, capillary permeability, and fibroblastic proliferation. It achieves potent suppression of the immune response by inhibiting the transcription of pro-inflammatory genes.
Tobramycin: A water-soluble aminoglycoside that irreversibly binds to the 30S subunit of the bacterial ribosome, inducing mRNA misreading. It exhibits excellent bactericidal activity, specifically functioning as a critical clinical tool against severe Gram-negative bacilli keratitis and conjunctivitis.
Indications
Treatment of bacterial conjunctivitis caused by susceptible organisms
Superficial ocular bacterial infections as advised by the treating ophthalmologist
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Notivol R, et al. Efficacy and safety of dexamethasone in ophthalmic suspensions. Am J Ophthalmol. 2004;137(4):780-781.
2. McGhee CN, et al. Locally administered ocular corticosteroids: benefits and risks. Drug Saf. 2002;25(1):33-55.
1. Wilhelmus KR, et al. Tobramycin drops vs ointment in ocular infections. Am J Ophthalmol. 1987;104(3):284-288.
Warning: This information is only for the use of registered medical practitioners only.
