Floxoptho T Eye Drops
Floxoptho T Eye Drops
Composition: Moxifloxacin 0.5% w/v + Tobramycin Sulphate 0.3% w/v
Formulation: Eye Drops
Category: Antibiotic + Antibiotic
Packaging: 5ML
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Floxoptho T Eye Drops
Description
Therapy/Class: Antibiotic + Antibiotic
Mechanism of Action:
Moxifloxacin: An 8-methoxy advanced generation fluoroquinolone that optimally inhibits both Topoisomerase II and Topoisomerase IV. The methoxy group at the C-8 position minimizes the selection of resistant mutants and broadens coverage against atypical, Gram-positive, and Gram-negative organisms in ocular infections.
Tobramycin: A water-soluble aminoglycoside that irreversibly binds to the 30S subunit of the bacterial ribosome, inducing mRNA misreading. It exhibits excellent bactericidal activity, specifically functioning as a critical clinical tool against severe Gram-negative bacilli keratitis and conjunctivitis.
Indications
Treatment of bacterial conjunctivitis caused by susceptible organisms
Superficial ocular bacterial infections as advised by the treating ophthalmologist
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Stroman DW, et al. In vitro and in vivo efficacy of moxifloxacin and gatifloxacin against ocular pathogens. Surv Ophthalmol. 2005;50 Suppl 1:S16-24.
2. O’Brien TP, et al. Antibacterial susceptibility of conjunctival bacterial isolates: A ten-year review. Clin Ophthalmol. 2007;1(3):341-348.
1. Wilhelmus KR, et al. Tobramycin drops vs ointment in ocular infections. Am J Ophthalmol. 1987;104(3):284-288.
Warning: This information is only for the use of registered medical practitioners only.
