Poloptho Eye Ointment
Poloptho Eye Ointment
Composition: Polymyxin B 10000IU + Chloramphenicol 1% w/w
Formulation: Eye Ointment
Category: Antibiotic
Packaging: 5GM
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Poloptho Eye Ointment
Description
Therapy/Class: Antibiotic
Mechanism of Action:
Polymyxin B: A bactericidal cyclic lipopeptide that targets and disrupts the outer cell membrane of Gram-negative bacilli. It binds to lipopolysaccharides, severely altering membrane permeability and causing osmotic lysis.
Chloramphenicol: A highly lipophilic, bacteriostatic agent that diffuses rapidly across ocular tissues, binding reversibly to the 50S ribosomal subunit to interrupt peptidyl transferase activity and block bacterial protein synthesis.
Indications
Treatment of bacterial conjunctivitis caused by susceptible organisms
Superficial ocular bacterial infections as advised by the treating ophthalmologist
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Extrude a 1/2 inch ribbon into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Fraunfelder FT, et al. Clinical Ocular Toxicology: Drugs, Chemicals, and Herbs. Elsevier Saunders; 2008.
2. American Academy of Ophthalmology Preferred Practice Pattern Guidelines. Ophthalmology. 2021.
Warning: This information is only for the use of registered medical practitioners only.
