Bromfenac: A highly potent, topically active nonsteroidal anti-inflammatory drug (NSAID) that halts the cyclooxygenase (COX-1 and COX-2) enzymatic pathways. The addition of a bromine atom enhances ocular tissue penetration (aqueous humor and target ciliary body) to effectively block prostaglandin biosynthesis, preventing prostaglandin-mediated miosis, hyperalgesia, and blood-aqueous barrier breakdown.
Indications
Management of post-surgical anterior segment inflammation
Reduction of ocular pain following ophthalmic surgery
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Donnenfeld ED, et al. Bromfenac ophthalmic solution 0.09% for postoperative ocular inflammation and pain. Ophthalmology. 2007;114(9):1625-1632.
2. Waterbury LD, et al. Inhibitory effect of bromfenac on cyclooxygenase enzymes. Invest Ophthalmol Vis Sci. 2006;47(13):1447.
Warning: This information is only for the use of registered medical practitioners only.
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Disclaimer: This content is compiled from various references. We do not endorse any of it. Readers are advised not to self-medicate and to follow a doctor’s prescription and guidance.