Floxagerm KT Eye Drops
Floxagerm KT Eye Drops
Composition: Ketorolac Tromethamine 0.5% w/v + Ofloxacin 0.3% w/v
Formulation: Eye Drops
Category: Antibiotic + NSAID
Packaging: 5ML
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Floxagerm KT Eye Drops
Description
Therapy/Class: Antibiotic + NSAID
Mechanism of Action:
Ofloxacin: A fluorinated carboxyquinolone exerting potent bactericidal activity by selectively inhibiting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. This action arrests DNA replication, transcription, and repair in a broad spectrum of Gram-positive and Gram-negative ocular pathogens.
Ketorolac Tromethamine: A direct, non-selective COX inhibitor that prevents the conversion of arachidonic acid to endoperoxides. This halts the prostaglandin-mediated inflammatory cascade, significantly raising the nociceptive threshold (reducing pain) and preventing surgically induced miosis and cystoid macular edema.
Indications
Treatment of bacterial conjunctivitis caused by susceptible organisms
Superficial ocular bacterial infections as advised by the treating ophthalmologist
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. O’Brien TP, et al. Efficacy of ofloxacin vs cefazolin and tobramycin in the therapy for bacterial keratitis. Arch Ophthalmol. 1995;113(10):1257-1265.
2. Osato MS, et al. Clinical applications of ofloxacin in ophthalmology. Am J Ophthalmol. 1989;108(4):514-515.
1. Flach AJ, et al. Effectiveness of ketorolac tromethamine 0.5% ophthalmic solution for chronic aphakic and pseudophakic cystoid macular edema. Am J Ophthalmol. 1987;103(4):479-486.
Warning: This information is only for the use of registered medical practitioners only.
