Floxoptho LP Eye Drops
Floxoptho LP Eye Drops
Composition: Loteprednol Etabonate 0.5% w/v + Moxifloxacin Hydrochloride eq to Moxifloxacin 0.5% w/v
Formulation: Eye Drops
Category: Antibiotic + Corticosteroid
Packaging: 5ML
Eye Care Focus
Trusted Eye Solutions
Quality Eye Products
Floxoptho LP Eye Drops
Description
Therapy/Class: Antibiotic + Corticosteroid
Mechanism of Action:
Moxifloxacin: An 8-methoxy advanced generation fluoroquinolone that optimally inhibits both Topoisomerase II and Topoisomerase IV. The methoxy group at the C-8 position minimizes the selection of resistant mutants and broadens coverage against atypical, Gram-positive, and Gram-negative organisms in ocular infections.
Loteprednol Etabonate: A retrometabolic, ester-based ‘soft’ corticosteroid structurally designed to provide potent localized immunosuppressive and anti-inflammatory effects, followed by predictable, rapid de-esterification into inactive carboxylic acid metabolites. This mechanism dramatically mitigates the propensity for steroid-induced intraocular pressure (IOP) elevation.
Indications
Treatment of bacterial conjunctivitis caused by susceptible organisms
Superficial ocular bacterial infections as advised by the treating ophthalmologist
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Stroman DW, et al. In vitro and in vivo efficacy of moxifloxacin and gatifloxacin against ocular pathogens. Surv Ophthalmol. 2005;50 Suppl 1:S16-24.
2. O’Brien TP, et al. Antibacterial susceptibility of conjunctival bacterial isolates: A ten-year review. Clin Ophthalmol. 2007;1(3):341-348.
1. Sheppard JD, et al. Loteprednol etabonate ophthalmic suspension 0.5% in the treatment of post-operative inflammation. Clin Ophthalmol. 2014;8:2101-2110.
Warning: This information is only for the use of registered medical practitioners only.
