Floxoptho P Eye Drops
Floxoptho P Eye Drops
Composition: Moxifloxacin 0.5% w/v + Prednisolone 1% w/v
Formulation: Eye Drops
Category: Antibiotic + Corticosteroid
Packaging: 5ML
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Floxoptho P Eye Drops
Description
Therapy/Class: Antibiotic + Corticosteroid
Mechanism of Action:
Moxifloxacin: An 8-methoxy advanced generation fluoroquinolone that optimally inhibits both Topoisomerase II and Topoisomerase IV. The methoxy group at the C-8 position minimizes the selection of resistant mutants and broadens coverage against atypical, Gram-positive, and Gram-negative organisms in ocular infections.
Prednisolone: A standard-of-care topical corticosteroid that binds to intracellular glucocorticoid receptors, modulating DNA transcription to inhibit edema, fibrin deposition, capillary dilation, leukocyte migration, and phagocytic activity associated with acute ocular inflammation.
Indications
Treatment of bacterial conjunctivitis caused by susceptible organisms
Superficial ocular bacterial infections as advised by the treating ophthalmologist
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Stroman DW, et al. In vitro and in vivo efficacy of moxifloxacin and gatifloxacin against ocular pathogens. Surv Ophthalmol. 2005;50 Suppl 1:S16-24.
2. O’Brien TP, et al. Antibacterial susceptibility of conjunctival bacterial isolates: A ten-year review. Clin Ophthalmol. 2007;1(3):341-348.
1. Leibowitz HM, et al. Human conjunctival response to topically applied corticosteroids. Arch Ophthalmol. 1984;102(2):272-276.
Warning: This information is only for the use of registered medical practitioners only.
