Hyperbinz T Eye Drops
Hyperbinz T Eye Drops
Composition: Brinzolamide 1% w/v + Timolol Maleate eq to Timolol 0.5% w/v
Formulation: Eye Drops
Category: Anti-Glaucoma
Packaging: 5ML
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Hyperbinz T Eye Drops
Description
Therapy/Class: Anti-Glaucoma
Mechanism of Action:
Timolol Maleate: A non-selective beta-1 and beta-2 adrenergic receptor antagonist lacking significant intrinsic sympathomimetic or membrane-stabilizing activity. It reliably decreases intraocular pressure by fundamentally reducing aqueous humor synthesis in the ciliary processes.
Brinzolamide: A specific, reversible, non-competitive inhibitor of carbonic anhydrase II (CA-II) in the ciliary epithelium. By slowing the formation of bicarbonate ions, it reduces sodium and fluid transport, directly inhibiting aqueous humor production.
Indications
Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma
Management of ocular hypertension
Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.
Dosage & Administration
Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.
Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.
References
1. Zimmerman TJ, et al. Timolol maleate: Efficacy and safety. Arch Ophthalmol. 1979;97(4):656-658.
2. Boger WP 3rd. Timolol: short term escape and long term drift. Ann Ophthalmol. 1979;11(8):1239-1242.
1. Sall K, et al. Clinical efficacy of brinzolamide 1% vs dorzolamide 2% in primary open-angle glaucoma. Surv Ophthalmol. 2000;44(Suppl 2):S155-S162.
Warning: This information is only for the use of registered medical practitioners only.
