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Poloptho DX Eye Drops

Composition: Polymyxin B Sulphate 5000 IU + Chloramphenicol 0.4% w/v + Dexamethasone Sodium Phosphate 0.1% w/v

Formulation: Eye Drops

Category: Antibiotic + Corticosteroid

Packaging: 5ML

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Poloptho DX Eye Drops

Description

Therapy/Class: Antibiotic + Corticosteroid

Mechanism of Action:

Dexamethasone: A highly efficacious, long-acting synthetic glucocorticoid that rapidly permeates the corneal epithelium to suppress cellular exudation, capillary permeability, and fibroblastic proliferation. It achieves potent suppression of the immune response by inhibiting the transcription of pro-inflammatory genes.

Polymyxin B: A bactericidal cyclic lipopeptide that targets and disrupts the outer cell membrane of Gram-negative bacilli. It binds to lipopolysaccharides, severely altering membrane permeability and causing osmotic lysis.

Chloramphenicol: A highly lipophilic, bacteriostatic agent that diffuses rapidly across ocular tissues, binding reversibly to the 50S ribosomal subunit to interrupt peptidyl transferase activity and block bacterial protein synthesis.

Indications

Treatment of bacterial conjunctivitis caused by susceptible organisms

Superficial ocular bacterial infections as advised by the treating ophthalmologist

Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.

Dosage & Administration

Instill 1 drop into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response and severity.

Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.

References

1. Notivol R, et al. Efficacy and safety of dexamethasone in ophthalmic suspensions. Am J Ophthalmol. 2004;137(4):780-781.

2. McGhee CN, et al. Locally administered ocular corticosteroids: benefits and risks. Drug Saf. 2002;25(1):33-55.

Warning: This information is only for the use of registered medical practitioners only.

Frequently Asked Questions

What type of formulation is Poloptho DX Eye Drops?

It is an ophthalmic anti-infective and anti-inflammatory eye drop formulation.

Which therapeutic category does Poloptho DX Eye Drops belong to?

It belongs to the ophthalmic antibiotic and corticosteroid combination therapeutic category.

How does Poloptho DX Eye Drops work?

It works by killing infection-causing bacteria and reducing eye inflammation.

How quickly does Poloptho DX Eye Drops start working?

Improvement in symptoms may be noticed within 24–48 hours of regular use.

Can contact lenses be worn while using Poloptho DX Eye Drops?

No, remove contact lenses before use and wait at least 15–20 minutes before reinserting.

Which eye conditions can Poloptho DX Eye Drops help manage?

It helps manage bacterial conjunctivitis, blepharitis, and infected inflammatory eye conditions.

How should Poloptho DX Eye Drops be used?

Use as directed by the doctor, usually 1–2 drops in the affected eye(s) while maintaining proper eye hygiene.

What is the recommended dosage for Poloptho DX Eye Drops?

Usually 1–2 drops in the affected eye(s) 2–4 times daily, or as prescribed by the doctor.

Can Poloptho DX Eye Drops be used after eye surgery?

Yes, it may be prescribed after eye surgery to help prevent infection and reduce inflammation.

What should patients know before using Poloptho DX Eye Drops?

Use it only as prescribed, avoid touching the dropper tip, and do not use it for longer than recommended by the doctor.

Certified Manufacturing Standards

Disclaimer: This content is compiled from various references. We do not endorse any of it. Readers are advised not to self-medicate and to follow a doctor’s prescription and guidance.