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Poloptho DX Eye Ointment

Composition: Polymyxin B Sulphate 10000 Units + Chloramphenicol 1% w/w + Dexamethasone Sodium Phosphate 0.1% w/w

Formulation: Eye Ointment

Category: Antibiotic + Corticosteroid

Packaging: 5GM

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Poloptho DX Eye Ointment

Description

Therapy/Class: Antibiotic + Corticosteroid

Mechanism of Action:

Dexamethasone: A highly efficacious, long-acting synthetic glucocorticoid that rapidly permeates the corneal epithelium to suppress cellular exudation, capillary permeability, and fibroblastic proliferation. It achieves potent suppression of the immune response by inhibiting the transcription of pro-inflammatory genes.

Polymyxin B: A bactericidal cyclic lipopeptide that targets and disrupts the outer cell membrane of Gram-negative bacilli. It binds to lipopolysaccharides, severely altering membrane permeability and causing osmotic lysis.

Chloramphenicol: A highly lipophilic, bacteriostatic agent that diffuses rapidly across ocular tissues, binding reversibly to the 50S ribosomal subunit to interrupt peptidyl transferase activity and block bacterial protein synthesis.

Indications

Treatment of bacterial conjunctivitis caused by susceptible organisms

Superficial ocular bacterial infections as advised by the treating ophthalmologist

Note: This is an indicative Indication, please follow the doctors advise. Do not self medicate.

Dosage & Administration

Extrude a 1/2 inch ribbon into the inferior conjunctival cul-de-sac of the affected eye(s) as prescribed by the physician. Dosing frequency should be adjusted according to clinical response.

Note: This is an indicative dosage, please follow the doctors advise. Do not self medicate.

References

1. Notivol R, et al. Efficacy and safety of dexamethasone in ophthalmic suspensions. Am J Ophthalmol. 2004;137(4):780-781.

2. McGhee CN, et al. Locally administered ocular corticosteroids: benefits and risks. Drug Saf. 2002;25(1):33-55.

Warning: This information is only for the use of registered medical practitioners only.

Frequently Asked Questions

What is the composition of Poloptho DX Eye Ointment?

Poloptho DX Eye Ointment contains Polymyxin B Sulphate 10,000 Units, Chloramphenicol 1% w/w and Dexamethasone Sodium Phosphate 0.1% w/w as active ingredients.

Which eye conditions can Poloptho DX Eye Ointment help manage?

It helps manage bacterial conjunctivitis, blepharitis, and infected inflammatory eye conditions.

Which therapeutic category does Poloptho DX Eye Ointment belong to?

It belongs to the category of ophthalmic anti-infective and anti-inflammatory combination therapies.

Can Poloptho DX Eye Ointment help reduce redness, irritation, or discomfort?

Yes, it helps reduce redness, swelling, irritation, and eye discomfort.

What should patients do if they miss a dose?

Apply it as soon as remembered, but skip it if the next dose is near. Do not use extra ointment to make up for the missed dose.

Does Poloptho DX Eye Ointment support long-term ocular care?

No, it is generally intended for short-term use unless advised otherwise by an eye specialist.

Should Poloptho DX Eye Ointment be used without medical advice?

No, it should only be used under a doctor’s supervision to ensure safe and appropriate treatment.

Can contact lenses be worn while using it?

No, contact lenses should be avoided during treatment unless advised by a doctor.

Can Poloptho DX Eye Ointment be used after eye surgery?

Yes, it may be prescribed after eye surgery to help prevent infection and reduce inflammation during recovery.

How is Poloptho DX Eye Ointment supplied?

It is supplied as a sterile ophthalmic ointment in a tube for application inside the eye as prescribed.

Certified Manufacturing Standards

Disclaimer: This content is compiled from various references. We do not endorse any of it. Readers are advised not to self-medicate and to follow a doctor’s prescription and guidance.